We describe the natural history of a three-month-old patient with Hunter Syndrome with hematopoietic stem cell transplant (HSCT) who developed recurrent diffuse alveolar hemorrhage (DAH) requiring extracorporeal membrane oxygenation (ECMO). The patient underwent HSCT with several complications, including veno-occlusive disease and DAH.

A recently reported novel reaction of acute respiratory distress syndrome (ARDS) often requiring Extracorporeal Membrane Oxygenation (ECMO) does not yet have specific radiographic findings reported. We report radiologic findings in 19 patients who developed ARDS after taking TMP-SMX.

A high school athlete got desperately sick and needed life support. Years later, she helped discover the cause of her rare illness.

A high school athlete got desperately sick and needed life support. Years later, she helped discover the cause of her rare illness.

We have identified an underrecognized severe adverse drug reaction (ADR) of trimethoprim-sulfamethoxazole (TMP-SMX) associated respiratory failure in previously healthy children and young adults.