Radiologic Findings in a Novel Diagnosis: Trimethoprim-Sulfamethoxazole in ARDS
A recently reported novel reaction of acute respiratory distress syndrome (ARDS) often requiring Extracorporeal Membrane Oxygenation (ECMO) does not yet have specific radiographic findings reported. We report radiologic findings in 19 patients who developed ARDS after taking TMP-SMX.
Her Lungs Mysteriously Shut Down. How Could This Have Happened?
A high school athlete got desperately sick and needed life support. Years later, she helped discover the cause of her rare illness.
HLA-B*07:02 and HLA-C*07:02 are associated with trimethoprim-sulfamethoxazole respiratory failure
We have identified an underrecognized severe adverse drug reaction (ADR) of trimethoprim-sulfamethoxazole (TMP-SMX) associated respiratory failure in previously healthy children and young adults.
Two Local Physicians Unlock Mystery of Lung Disease and Death in Teens
You've probably heard about the extremely popular antibiotic known as "Bactrim," which is used to treat all kinds of ailments from acne to urinary tract infections. But two local physicians recently figured out - that for some teenagers - the common prescription can lead to devastating reactions, including death.
Trimethoprim-Sulfamethoxazole-associated Fulminant Respiratory Failure in Children and Young Adults
Here we describe 14 previously healthy children and young adults exposed to TMP-SMX before the development of fulminant respiratory failure, potentially reflecting a previously unappreciated, life-threatening ADR to TMP-SMX.
Researchers’ Quest to Explain Popular Antibiotic Link to Respiratory Illness
Zei Uwadia made national headlines in 2018 when she walked the halls of Children's Mercy Kansas City while on life support. All told, she spent more than six months connected to an extracorporeal membrane oxygenation (ECMO) machine while battling a mysterious lung ailment. That work focuses on trimethoprim-sulfamethoxazole, more commonly known as Bactrim
A true inspiration
Carson Dodd is still hooping while receiving the highest form of life support after his lungs failed.
FDA issues new warning following Springfield
A young girl from Springfield had lung failure shortly after taking a very common antibiotic, Bactrim. Since then, the FDA is issuing a new warning of acute respiratory failure associated with that drug, which some patients believe caused death.
Did a common drug play a role in teen’s death
Doctors from Children's Mercy in Kansas City published a medical study in the Pediatrics journal. They studied five previously healthy young patients. Of the five patients in the study, two died, four were considered for organ transplants and all experienced lung failure.
Trimethoprim-sulfamethoxazole linked to ARDS
Trimethoprim-sulfamethoxazole (TMP-SMX) treatment may be linked to the onset of severe acute respiratory distress syndrome (ARDS) in adolescents, according to a recent case series published online May 31 in Pediatrics.
Severe Acute Respiratory Failure in Healthy Adolescents Exposed to Trimethoprim-Sulfamethoxazole
Pulmonary toxicity induced by trimethoprim-sulfamethoxazole (TMP-SMX) has been described, although the disease process is poorly understood.
Severe Respiratory Failure Strikes Healthy Teens on Trimethoprim-sulfamethoxazole
Trimethoprim-sulfamethoxazole was linked to severe respiratory distress syndrome in five previously healthy teens, two of whom died.
Inside Pediatrics Season 3: Zei’s Story
A documentary from Children’s Mercy Kansas City about the story of Zei Uwadia and her long battle with ECMO.